Johnson & Johnson Negotiates $20 Billion Sale of DePuy Synthes Orthopedics Unit to Apollo Global Management

Here's what it means for you.
This potential divestiture could reshape the healthcare investment landscape, impacting market dynamics and growth strategies.
What happened
Johnson & Johnson is in exclusive negotiations to sell its DePuy Synthes orthopedics business to Apollo Global Management for approximately $20 billion.
The Context
- Strategic Shift: J&J aims to focus on higher-growth areas like oncology and immunology, moving away from slower-growing segments like orthopedics.
- Revenue Impact: The DePuy Synthes unit generated $9.3 billion in revenue in 2025, representing less than 10% of J&J's total revenue.
- Ongoing Talks: Discussions are preliminary and non-binding, with the possibility of other bidders or a spin-off structure still on the table.
The Number
— This figure highlights the significant revenue generated by the DePuy Synthes unit, underscoring its importance in J&J's overall portfolio and the stakes involved in the potential sale.
Takeaway
If completed, this deal could mark one of the largest private equity transactions in healthcare, influencing future investment strategies in the sector.
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