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    Moderna Shares Plummet Following Leak of Melanoma Vaccine Trial Data

    Section editor: ·High6 articles covering this·6 news sources·Updated 2 hours ago·World
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    A graphic illustrating Moderna's stock decline and melanoma vaccine trial results.

    What happened

    Moderna shares plummeted after leaked Phase 3 trial data for its melanoma vaccine fell short of Wall Street expectations.

    The Context

    • Data Leak: The trial results were prematurely released via Oncology Central, leading to chaotic trading and a swift market reaction.
    • Efficacy Results: The mRNA vaccine combined with Keytruda showed a 42% reduction in recurrence or death, aligning with prior signals but disappointing investor expectations.
    • Market Impact: Moderna's stock dropped as much as 25% intraday, erasing approximately $24 billion in market capitalization, while Merck's shares dipped modestly.

    The Number

    25%

    — This peak intraday decline in Moderna shares highlights the volatility and risk associated with biotech investments, particularly around clinical trial outcomes.

    Takeaway

    As the market stabilizes, focus will shift to upcoming presentations and the implications for future cancer therapies.

    6 Articles
    Financial Times

    Moderna shares sink after leaked cancer data missed expectations

    Moderna's shares experienced a significant decline after the company announced that its melanoma vaccine treatment, which reduced the risk of recurrence or death by 58%, did not meet Wall Street's high expectations. This news led to a drop in investo...

    TheStreet

    Moderna stock’s 17% slump was a ‘sell the news’ event, analyst says

    Moderna's stock experienced a significant 17% decline following the leak of trial data for its personalized mRNA cancer vaccine, developed in collaboration with Merck, which showed promising results but failed to meet Wall Street's high expectations.

    Dow Jones – Health

    Moderna shares plunged after details from a closely guarded mRNA-based cancer vaccine study were shared on social media

    Moderna's shares experienced a significant decline after confidential details from a study on its mRNA-based cancer vaccine were leaked on social media ahead of an anticipated conference. The study was expected to provide critical insights into the v...

    10 hours ago
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    The Wall Street Journal

    Moderna’s Stock Plummets After Cancer-Vaccine Data Shared on Social Media

    Moderna's stock experienced a significant decline of up to 25% following the unauthorized sharing of data from a closely guarded study regarding its personalized mRNA cancer vaccine. This data was expected to be formally presented at an upcoming conf...

    10 hours ago
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    International Business Times

    Details of Moderna's Breakthrough Cancer Vaccine Got Leaked. Its Stock is Plunging.

    Moderna's stock plummeted by up to 25% following the leak of data regarding its experimental cancer vaccine, despite the information being more favorable than Wall Street's expectations. This unexpected decline raises concerns about investor confiden...

    11 hours ago
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    Forbes

    Moderna Stock Plunges 25% After Possible Cancer Vaccine Data Leak

    Moderna's stock plummeted by 25% following a potential data leak regarding its personalized cancer vaccine, marking a significant downturn after a previously strong stock rally in 2026 driven by optimism about the vaccine's prospects.

    12 hours ago
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